Animal-Free Recombinant Human SDF-1α (CXCL12) 0 评论Submit a Review 产品详情 产品编号: AF-300-28A 产品描述: SDF-1α and β are stromal-derived, CXC chemokines that signal through the CXCR4 receptor. SDF-1α and β chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells. Additionally, the SDF-1 proteins exert HIV-suppressive activity in cells expressing the CXCR4 receptor. Human and murine SDF-1 proteins act across species. SDF-1α and β contain the four highly conserved cysteine residues present in CXC chemokines. The mature SDF-1α protein is the result of alternative splicing of the SDF-1 gene and contains 68 amino acid residues. Recombinant Human SDF-1α is an 8.0 kDa protein containing 68 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Stromal-Cell Derived Factor-1, CXCL12, PBSF AA Sequence: KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Calculated Molecular Weight: 8 kDa Biological Activity: Determined by its ability to chemoattract IL-2-activated human T cells using a concentration range of 20.0-80.0 ng/ml. Accession Number: P48061 Gene ID: 6387 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Mouse References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest 艾滋病/HIV 化学趋化 免疫系统 炎症 神经生物学 干细胞&分化 创伤修复 product.subtitle.recentcitations 第一作者 Egea, V 标题 Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release. 文献引用 Cell Death & Disease; 12(6) pg516 PubMed Id 34016957 第一作者 Weston, C J 标题 Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis. 文献引用 The Journal of Clinical Investigation; 125(2) pg501-20 PubMed Id 25562318 第一作者 Timár, C I 标题 Antibacterial effect of microvesicles released from human neutrophilic granulocytes. 文献引用 Blood; 121(3) pg510-8 PubMed Id 23144171