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趋化因子

Recombinant Murine MIP-3β (CCL19)

产品详情

产品编号: 250-27B
产品描述:
Recombinant Murine MIP-3β (CCL19)

MIP-3β is a CC chemokine, expressed in the thymus, lymph nodes, and in activated bone marrow stromal cells that signals through the CCR7 receptor. MIP-3β is a chemoattractant for T and B lymphocytes, and myeloid progenitor cells. Human MIP-3β is active on murine cells. Recombinant Murine MIP-3β is a 9.2 kDa protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-3β, CCL19, ELC, Exodus-3, SCYA19

AA Sequence: GANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract activated human T cells expressing the CCR7 receptor. The ED50 for this effect is 30-90 ng/ml.

Calculated Molecular Weight: 9.2 kDa

Accession Number: O70460

Gene ID: 24047

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

第一作者
Tse, B C
标题
Exposure to Systemic Immunosuppressive Ultraviolet Radiation Alters T Cell Recirculation through Sphingosine-1-Phosphate.
文献引用
Journal of immunology (Baltimore, Md. : 1950); 207(9) pg2278-2287
PubMed Id
第一作者
Qin, T
标题
Mucosal Vaccination for Influenza Protection Enhanced by Catalytic Immune-Adjuvant.
文献引用
Advanced science (Weinheim, Baden-Wurttemberg, Germany); 7(18) pg2000771
PubMed Id
第一作者
Cain, D W
标题
Murine Glucocorticoid Receptors Orchestrate B Cell Migration Selectively between Bone Marrow and Blood.
文献引用
Journal of immunology (Baltimore, Md. : 1950); 205(3) pg619-629
PubMed Id

product.subtitle.productreviews

现有评论
migration assays
works well for dendritic cells in migration assays!
来自:  Caitlin | 日期:  2020/7/13