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Recombinant Human FGF-5

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Product Details

Catalogue Number: 100-34
Description:
Recombinant Human FGF-5

FGF-5 is a secreted, heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-5 binds to FGFR 1c and 2c, and plays a regulatory role in the hair growth cycle. Recombinant Human FGF-5 is a 27.6 kDa protein consisting of 252 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-5, HBGF-5, Smag-82

AA Sequence: MAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8). The expected ED50 is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.

Calculated Molecular Weight: 27.6 kDa

Accession Number: P12034

Gene ID: 2250

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Hu, H
Title
Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.
Citation
Cancer Cell; 39(11) pg1531-1547.e10
PubMed Id
First Author
Savchenko, E
Title
FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes.
Citation
Scientific Reports; 9(1) pg9610
PubMed Id
First Author
Westphal, S
Title
Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes.
Citation
Scientific Reports; 9(1) pg8470
PubMed Id