Recombinant Human FGF-acidic 0 ReviewsSubmit a Review Product Details Catalogue Number: 100-17A Description: FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant Human FGF-acidic is a 16.8 kDa protein consisting of 141 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-acidic, FGF-1, HBGF-1, ECGF-beta AA Sequence: MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.5 ng/ml in the presence of 10 µg/ml heparin, corresponding to a specific activity of ≥ 2 x 106 units/mg. Calculated Molecular Weight: 16.8 kDa Accession Number: P05230 Gene ID: 2246 crossreactivity: Cow, Hagfish, Hamster, Human, Leech, Mouse, Pig, Rat, Shark, Squid References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer Cell Culture FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations First Author Zhang, X Title Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. Citation The Journal of Biological Chemistry; 281(23) pg15694-700 PubMed Id 16597617 First Author Vanhove, J Title H3K27me3 Does Not Orchestrate the Expression of Lineage-Specific Markers in hESC-Derived Hepatocytes In Vitro. Citation Stem Cell Reports; 7(2) pg192-206 PubMed Id 27477635 First Author Hu, H Title Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms. Citation Cancer Cell; 39(11) pg1531-1547.e10 PubMed Id 34624218
