Chemokines

Recombinant Human GRO-β (CXCL2)

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Product Details

Catalogue Number: 300-39
Description:


Recombinant Human GRO-beta (CXCL2)

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Human GRO-β is a 7.9 kDa protein consisting of 73 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSAβ), CXCL2, MIP-2α, GRO2

AA Sequence: APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 7.9 kDa

Accession Number: P19875

Gene ID: 2920

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Tiffany, H L
Title
Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309.
Citation
The Journal of Experimental Medicine; 186(1) pg165-70
PubMed Id
First Author
Bouhaddou, M
Title
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
Citation
Cell; 182(3) pg685-712.e19
PubMed Id
First Author
Li, Q
Title
mRNA-engineered mesenchymal stromal cells expressing CXCR2 enhances cell migration and improves recovery in IBD.
Citation
Molecular therapy. Nucleic acids; 26 pg222-236
PubMed Id