Chemokines

Recombinant Human IL-8 (CXCL8) (77 a.a.)

Product Details

Catalogue Number: 200-08
Description:

IL-8 is a proinflammatory CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is secreted by monocytes and endothelial cells. IL-8 chemoattracts and activates neutrophils. Recombinant Human IL-8 (CXCL8) (77 a.a.) (endothelial-derived) is an 8.9 kDa protein containing 77 amino acid residues.

Source: E.coli

Synonyms: Interleukin-8, CXCL8, monocyte-derived neutrophil chemotactic factor (MDNCF), neutrophil activating factor (NAF), NAP-1

AA Sequence: AVLPRSAKEL RCQCIKTYSK PFHPKFIKEL RVIESGPHCA NTEIIVKLSD GRELCLDPKE NWVQRVVEKF LKRAENS

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human peripheral blood neutrophils using a concentration range of 25.0-150.0 ng/ml.

Calculated Molecular Weight: 8.9 kDa

Accession Number: P10145

Gene ID: 3576

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Qi, J
Title
Fibrin regulation of interleukin-8 gene expression in human vascular endothelial cells.
Citation
Blood; 90(9) pg3595-602
PubMed Id
First Author
Wang, W
Title
Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer
Citation
Nature Communications; 12(1) pg4441
PubMed Id
First Author
Jain, P
Title
Reconstruction of Ultra-thin Alveolar-capillary Basement Membrane Mimics.
Citation
Advanced Biology; 5(8) pge2000427
PubMed Id