FGF‐basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF‐basic is a non‐glycosylated, heparin‐binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF‐basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Bovine FGF‐basic is a 17.1 kDa protein consisting of 154 amino acid residues.
Manufactured using all Animal-Free reagents.
Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
AAGSITTLPS LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYS SWYVALKRTG QYKLGPKTGP GQKAILFLPM SAKS
≥ 95% by SDS-PAGE gel and HPLC analyses.
Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Calculated Molecular Weight:
Not for human use.