Recombinant Murine Exodus-2 (CCL21) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-13 Description: Exodus-2 is a CC chemokine that can signal through the CCR7 receptor. It is expressed in lymphatic endothelial cells, the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant Murine Exodus-2 is a 12.0 kDa protein containing 110 amino acid residues. Source: E.coli Synonyms: CCL21, 6Ckine, SLC AA Sequence: SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 12 kDa Accession Number: P86793 Gene ID: 65956 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. crossreactivity: Bacteria, Human, Human + Mouse, Leech, Monkey, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations First Author Chang, M H Title Arthritis flares mediated by tissue-resident memory T cells in the joint. Citation Cell Reports; 37(4) pg109902 PubMed Id 34706228 First Author Arasa, J Title Upregulation of VCAM-1 in lymphatic collectors supports dendritic cell entry and rapid migration to lymph nodes in inflammation. Citation The Journal of Experimental Medicine; 218(7) PubMed Id 33988714 First Author Riegel, K Title RAF kinases are stabilized and required for dendritic cell differentiation and function Citation Cell Death and Differentiation; 27(4) pg1300-1315 PubMed Id 31541179
