Recombinant Rat IL-2 0 ReviewsSubmit a Review Product Details Catalogue Number: 400-02 Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant Rat IL-2 is a 15.3 kDa protein containing 134 amino acid residues. Source: E.coli Synonyms: T-cell growth factor (TCGF), Aldesleukin AA Sequence: MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAIAQSI ISTM Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 as determined by the dose-dependent stimulation of the proliferation of murine CTLL-2 cells is ≤ 0.4 ng/ml, corresponding to a specific activity of ≥ 2.5 x 106 units/mg. Calculated Molecular Weight: 15.3 kDa Accession Number: P17108 Gene ID: 116562 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell COVID-19 AIDS/HIV Cancer Cell Culture Diabetes/Weight Regulation Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Allergy Transplantation product.subtitle.recentcitations First Author Kim, B Title Tubulosine selectively inhibits JAK3 signalling by binding to the ATP-binding site of the kinase of JAK3 Citation Journal of Cellular and Molecular Medicine; 24(13) pg7427-7438 PubMed Id 32558259 First Author Ma, B Title Combining Exosomes Derived from Immature DCs with Donor Antigen-Specific Treg Cells Induces Tolerance in a Rat Liver Allograft Model. Citation Scientific Reports; 6 pg32971 PubMed Id 27640806 First Author Hara, N Title Prevention of virus-induced type 1 diabetes with antibiotic therapy. Citation Journal of immunology (Baltimore, Md. : 1950); 189(8) pg3805-14 PubMed Id 22988033
