Chemokines

Recombinant Murine C10 (CCL6)

제품 상세

카다로그 번호 250-06
제품 설명

Murine C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues. Recombinant Murine C-10 is a 10.7 kDa protein containing 95 amino acid residues.

Source: E.coli

Synonyms: CCL6, MRP-1

AA Sequence: GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract Balb/c mouse spleen MNCs using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 10.7 kDa

Accession Number: P27784

Gene ID: 20305

Cross Reactivity:
Bacteria, Human , Mouse
Research Interest
Immune System Wound Healing Chemotaxis
References References
PubMed PubMed
SDS SDS
Product Line Product Line

Country Of Origin: USA

Not for human use.