Animal-Free Recombinant Human FGF-basic (146 a.a.) 1 AvisSubmit a Review Détails du Produit Catalog Number: AF-100-18C Description: FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Human FGF-basic (146 a.a.) is a 16.4 kDa protein consisting of 146 amino acid residues. Manufactured using all Animal-Free reagents. Source: E.coli Synonyms: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin AA Sequence: PALPEDGGSG AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH IKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTD ECFFFERLES NNYNTYRSRK YTSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg. Calculated Molecular Weight: 16.4 kDa Accession Number: P09038 Gene ID: 2247 Endotoxin: Endotoxin level is < 0.01 ng/ug of protein (< 0.1 EU/ug) crossreactivity: Human, Mouse References PubMed SDS Recherche de CoA Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer Cell Culture FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing Diabetes/Weight Regulation product.subtitle.recentcitations Premier Auteur Tang, Q Titre Alpha-Synuclein defects autophagy by impairing SNAP29-mediated autophagosome-lysosome fusion Citation Cell Death & Disease; 12(10) pg854 Id PubMed 34535638 Premier Auteur Gupta, B Titre The transcription factor ZEB1 regulates stem cell self-renewal and cell fate in the adult hippocampus. Citation Cell Reports; 36(8) pg109588 Id PubMed 34433050 Premier Auteur Zhu, T Titre ETV4 promotes breast cancer cell stemness by activating glycolysis and CXCR4-mediated sonic Hedgehog signaling. Citation Cell Death Discovery; 7(1) pg126 Id PubMed 34052833 product.subtitle.productreviews Avis existants FGF Basic for for Organoid Culture Used FGF-2 for Head and Neck squamous Cell Carcinoma Organoid Culture.Quick Overnight Delivery is great.Works great for organoid culture. De: Hardik | Date: 31/08/2020 × FGF Basic for for Organoid Culture Used FGF-2 for Head and Neck squamous Cell Carcinoma Organoid Culture.Quick Overnight Delivery is great.Works great for organoid culture. De: Hardik | Date: 31/08/2020 Close