Recombinant Murine IL-5 0 评论Submit a Review 产品详情 产品编号: 215-15 产品描述: IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant Murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains. Source: E.coli Synonyms: EDF, BCDFII, TRF AA Sequence: MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 105 units/mg. Calculated Molecular Weight: 26.2 kDa Accession Number: P04401 Gene ID: 16191 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Mouse References PubMed SDS CoA 搜索 Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 免疫系统 炎症 创伤修复 过敏 product.subtitle.recentcitations 第一作者 Wigton, E J 标题 MicroRNA-directed pathway discovery elucidates an miR-221/222-mediated regulatory circuit in class switch recombination. 文献引用 The Journal of Experimental Medicine; 218(11) PubMed Id 34586363 第一作者 Onodera, T 标题 A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site. 文献引用 Immunity; 54(10) pg2385-2398.e10 PubMed Id 34508662 第一作者 Patial, S 标题 Myeloid-IL4Rα is an indispensable link in IL-33-ILCs-IL-13-IL4Rα axis of eosinophil recruitment in murine lungs. 文献引用 Scientific Reports; 11(1) pg15465 PubMed Id 34326406