Recombinant Human FGF-9 0 ReviewsSubmit a Review Product Details Catalogue Number: 100-23 Description: FGF-9 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-9 targets glial cells, astrocytes cells and other cells that express FGFR 1c, 2c, 3b, 3c, and 4. Recombinant Human FGF-9 is a 23.2 kDa protein consisting of 206 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-9, GAF (Glia-activating factor), HBGF-9 AA Sequence: PLGEVGNYFG VQDAVPFGNV PVLPVDSPVL LSDHLGQSEA GGLPRGPAVT DLDHLKGILR RRQLYCRTGF HLEIFPNGTI QGTRKDHSRF GILEFISIAV GLVSIRGVDS GLYLGMNEKG ELYGSEKLTQ ECVFREQFEE NWYNTYSSNL YKHVDTGRRY YVALNKDGTP REGTRTKRHQ KFTHFLPRPV DPDKVPELYK DILSQS Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 units/mg. Calculated Molecular Weight: 23.2 kDa Accession Number: P31371 Gene ID: 2254 Note: 1mg will be provided as 2x500μg. crossreactivity: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations First Author Zhang, X Title Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. Citation The Journal of Biological Chemistry; 281(23) pg15694-700 PubMed Id 16597617 First Author Hu, H Title Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms. Citation Cancer Cell; 39(11) pg1531-1547.e10 PubMed Id 34624218 First Author Savchenko, E Title FGF family members differentially regulate maturation and proliferation of stem cell-derived astrocytes. Citation Scientific Reports; 9(1) pg9610 PubMed Id 31270389
