Recombinant Human FGF-9 0 ReviewsSubmit a Review Product Details Catalogue Number: 100-23 Description: FGF-9 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-9 targets glial cells, astrocytes cells and other cells that express FGFR 1c, 2c, 3b, 3c, and 4. Recombinant Human FGF-9 is a 23.2 kDa protein consisting of 206 amino acid residues. Source: E.coli Synonyms: Fibroblast Growth Factor-9, GAF (Glia-activating factor), HBGF-9 AA Sequence: PLGEVGNYFG VQDAVPFGNV PVLPVDSPVL LSDHLGQSEA GGLPRGPAVT DLDHLKGILR RRQLYCRTGF HLEIFPNGTI QGTRKDHSRF GILEFISIAV GLVSIRGVDS GLYLGMNEKG ELYGSEKLTQ ECVFREQFEE NWYNTYSSNL YKHVDTGRRY YVALNKDGTP REGTRTKRHQ KFTHFLPRPV DPDKVPELYK DILSQS Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors. The expected ED50 is ≤ 0.5 ng/ml corresponding to a specific activity of ≥ 2 x 106 units/mg. Calculated Molecular Weight: 23.2 kDa Accession Number: P31371 Gene ID: 2254 Note: 1mg will be provided as 2x500μg. crossreactivity: Human, Mouse, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Organoids Angiogenesis/Cardiovascular Bone, Skeletal, Cartilage Cancer FGF Superfamily Immune System Inflammation Neurobiology Stem Cells & Differentiation Wound Healing product.subtitle.recentcitations First Author Hu, H Title Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms. Citation Cancer Cell; 39(11) pg1531-1547.e10 PubMed Id 34624218 First Author Zhang, D Title Targeting local lymphatics to ameliorate heterotopic ossification via FGFR3-BMPR1a pathway Citation Nature Communications; 12(1) pg4391 PubMed Id 34282140 First Author Bantounas, I Title The miR-199a/214 Cluster Controls Nephrogenesis and Vascularization in a Human Embryonic Stem Cell Model. Citation Stem Cell Reports; 16(1) pg134-148 PubMed Id 33306987
