Recombinant Human IL-7 0 ReviewsSubmit a Review Product Details Catalogue Number: 200-07 Description: IL-7 is a hematopoietic growth factor that primarily affects early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors, such as ConA and IL-2. Human and murine IL-7 are cross-species reactive. Recombinant Human IL-7 is a 17.5 kDa protein containing 153 amino acid residues. Source: E.coli AA Sequence: MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH Synonyms: Interleukin-7, Lymphopoietin 1(LP-1), pre-B cell factor Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: The ED50 was determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 17.5 kDa Accession Number: P13232 Gene ID: 3574 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. crossreactivity: Bacteria, Human, Human + Hamster, Human + Mouse, Human + Virus, Monkey, Mouse, Mouse + Human, Rabbit, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest CAR T Cell Cancer Immune System Inflammation Stem Cells & Differentiation product.subtitle.recentcitations First Author Wang, W Title Hepatobiliary Tumor Organoids Reveal HLA Class I Neoantigen Landscape and Antitumoral Activity of Neoantigen Peptide Enhanced with Immune Checkpoint Inhibitors. Citation Advanced science (Weinheim, Baden-Wurttemberg, Germany); 9(22) pge2105810 PubMed Id 35665491 First Author Loef, E J Title Plasminogen and plasmin can bind to human T cells and generate truncated CCL21 that increases dendritic cell chemotactic responses. Citation The Journal of Biological Chemistry; 298(7) pg102112 PubMed Id 35690148 First Author Moosmann, C Title Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair. Citation STAR Protocols; 3(1) pg101031 PubMed Id 34977677
