Chemokine

Recombinant Rat GRO/KC (CXCL1)

Product Details

Catalogue Number: 400-10
Description:

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Rat GRO/KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: MGSAα, CXCL1, NAP-3, GRO1, GRO/MGSA (human), KC (murine), CINC (rat)

AA Sequence: APVANELRCQ CLQTVAGIHF KNIQSLKVMP PGPHCTQTEV IATLKNGREA CLDPEAPMVQ KIVQKMLKGV PK

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract rat neutrophils using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 7.8 kDa

Accession Number: P14095

Gene ID: 81503

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Robinson, S
Title
The chemokine growth-regulated oncogene-alpha promotes spinal cord oligodendrocyte precursor proliferation.
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The Journal of neuroscience : the official journal of the Society for Neuroscience; 18(24) pg10457-63
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First Author
McWilliam, A S
Title
Dendritic cells are recruited into the airway epithelium during the inflammatory response to a broad spectrum of stimuli.
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The Journal of Experimental Medicine; 184(6) pg2429-32
PubMed Id
First Author
Cai, Y
Title
Immunological characterization of HM5023507, an orally active PI3Kδ/γ inhibitor.
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Pharmacology Research and Perspectives; 8(1) pge00559
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