Recombinant Human Lymphotactin (XCL1) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-20 Description: Lymphotactin is the only known member of the C chemokine family, and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes, but not towards monocytes or neutrophils. Recombinant Human Lymphotactin is a 10.0 kDa protein consisting of 92 amino acid residues. Source: E.coli Synonyms: XCL-1, SCM-1a, ATAC AA Sequence: GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to bind α9 integrin expressed on the surface of MOLT4 cells. Calculated Molecular Weight: 10 kDa Accession Number: P47992 Gene ID: 6375 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) Note: 1mg will be provided as 2x500μg. crossreactivity: Bacteria, Hamster, Human, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Abdullah Zubir, A Z Title The chemokine lymphotactin and its recombinant variants in oral cancer cell regulation Citation Oral Diseases; PubMed Id 32562323 First Author Buskermolen, J K Title Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets. Citation Journal of Cellular Physiology; 232(11) pg2996-3005 PubMed Id 28387445 First Author Matsumoto, N Title A Novel α9 Integrin Ligand, XCL1/Lymphotactin, Is Involved in the Development of Murine Models of Autoimmune Diseases. Citation Journal of immunology (Baltimore, Md. : 1950); 199(1) pg82-90 PubMed Id 28550205
