Recombinant Human Lymphotactin (XCL1) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-20 Description: Lymphotactin is the only known member of the C chemokine family, and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes, but not towards monocytes or neutrophils. Recombinant Human Lymphotactin is a 10.0 kDa protein consisting of 92 amino acid residues. Source: E.coli Synonyms: XCL-1, SCM-1a, ATAC AA Sequence: GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to bind α9 integrin expressed on the surface of MOLT4 cells. Calculated Molecular Weight: 10 kDa Accession Number: P47992 Gene ID: 6375 Note: 1mg will be provided as 2x500μg. crossreactivity: Bacteria, Hamster, Human, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Sakthivel, S K Title CXCL10 blockade protects mice from cyclophosphamide-induced cystitis. Citation Journal of Immune Based Therapies and Vaccines; 6 pg6 PubMed Id 18957084 First Author Alexander-Brett, J M Title Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor. Citation The Journal of Experimental Medicine; 204(13) pg3157-72 PubMed Id 18070938 First Author Bleul, C C Title B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement. Citation The Journal of Experimental Medicine; 187(5) pg753-62 PubMed Id 9480985
