Chemokines

Recombinant Human Lymphotactin (XCL1)

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Product Details

Catalogue Number: 300-20
Description:


Recombinant Human Lymphotactin (XCL1)

Lymphotactin is the only known member of the C chemokine family, and signals through the receptor XCR1, formally known as GPR5. The spleen shows the highest level of lymphotactin compared to peripheral leukocytes, lung, colon and small intestine. Lymphotactin is chemotactic towards lymphocytes, but not towards monocytes or neutrophils. Recombinant Human Lymphotactin is a 10.0 kDa protein consisting of 92 amino acid residues.

Source: E.coli

Synonyms: XCL-1, SCM-1a, ATAC

AA Sequence: GSEVSDKRTC VSLTTQRLPV SRIKTYTITE GSLRAVIFIT KRGLKVCADP QATWVRDVVR SMDRKSNTRN NMIQTKPTGT QQSTNTAVTL TG

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to bind α9 integrin expressed on the surface of MOLT4 cells.

Calculated Molecular Weight: 10 kDa

Accession Number: P47992

Gene ID: 6375

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Sakthivel, S K
Title
CXCL10 blockade protects mice from cyclophosphamide-induced cystitis.
Citation
Journal of Immune Based Therapies and Vaccines; 6 pg6
PubMed Id
First Author
Alexander-Brett, J M
Title
Dual GPCR and GAG mimicry by the M3 chemokine decoy receptor.
Citation
The Journal of Experimental Medicine; 204(13) pg3157-72
PubMed Id
First Author
Bleul, C C
Title
B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagement.
Citation
The Journal of Experimental Medicine; 187(5) pg753-62
PubMed Id