Recombinant Human NAP-2 (CXCL7) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-14 Description: NAP-2 is a CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. It is produced in leukocytes by enzymatic processing of a precursor called platelet basic protein (PBP). NAP-2 chemoattracts and activates neutrophils. Recombinant Human NAP-2 protein is a 7.6 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines, and also the “ELR” motif, common to CXC chemokines that bind to CXCR1 and CXCR2. Source: E.coli Synonyms: Neutrophil Activating Protein-2, CXCL7, PBP (parent molecule), CTAP-III (precursor) AA Sequence: AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDESAD Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 7.6 kDa Accession Number: P02775 Gene ID: 5473 crossreactivity: Bacteria, Hamster, Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Tiffany, H L Title Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309. Citation The Journal of Experimental Medicine; 186(1) pg165-70 PubMed Id 9207005 First Author Di Giorgio, F P Title Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation. Citation Cell Stem Cell; 3(6) pg637-48 PubMed Id 19041780 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871
