Recombinant Murine MIG (CXCL9) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-18 Description: MIG, a CXC chemokine, is produced by IFN-γ stimulated monocytes, macrophages and endothelial cells. It signals through the CXCR3 receptor. MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities, including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors. Human MIG is active on murine cells. Recombinant Murine MIG is a 12.2 kDa protein containing 105 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines. Source: E.coli Synonyms: Monokine Induced by Interferon-gamma, CXCL9 AA Sequence: TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 50.0-150.0 ng/ml. Calculated Molecular Weight: 12.2 kDa Accession Number: P18340 Gene ID: 17329 crossreactivity: Bacteria, Human, Monkey, Mouse, References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Wound Healing Transplantation product.subtitle.recentcitations First Author Shin, H Title CD301b+ dendritic cells stimulate tissue-resident memory CD8+ T cells to protect against genital HSV-2. Citation Nature Communications; 7 pg13346 PubMed Id 27827367 First Author Thompson, B D Title Inhibition of G alpha i2 activation by G alpha i3 in CXCR3-mediated signaling. Citation The Journal of Biological Chemistry; 282(13) pg9547-55 PubMed Id 17289675 First Author Sakthivel, S K Title CXCL10 blockade protects mice from cyclophosphamide-induced cystitis. Citation Journal of Immune Based Therapies and Vaccines; 6 pg6 PubMed Id 18957084
