Recombinant Human IP-10 (CXCL10) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-12 Description: IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant Human IP-10 is an 8.6 kDa protein consisting of 77 amino acids, including the four conserved cysteine residues present in CXC chemokines. Source: E.coli Synonyms: γ-Interferon Inducible Protein 10, CXCL10, crg-2 AA Sequence: VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human T-Lymphocytes using a concentration of 10-50 ng/ml. Calculated Molecular Weight: 8.6 kDa Accession Number: P02778 Gene ID: 3627 crossreactivity: Bacteria, Human, Human + Hamster, Leech, Monkey, Mouse, Pig References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy Transplantation product.subtitle.recentcitations First Author Shen, H Title Intrinsic human immunodeficiency virus type 1 resistance of hematopoietic stem cells despite coreceptor expression. Citation Journal of Virology; 73(1) pg728-37 PubMed Id 9847379 First Author Agostini, C Title Involvement of the IP-10 chemokine in sarcoid granulomatous reactions. Citation Journal of immunology (Baltimore, Md. : 1950); 161(11) pg6413-20 PubMed Id 9834133 First Author Petersen, F Title A chondroitin sulfate proteoglycan on human neutrophils specifically binds platelet factor 4 and is involved in cell activation. Citation Journal of immunology (Baltimore, Md. : 1950); 161(8) pg4347-55 PubMed Id 9780212
