Chemokines

Recombinant Murine MIG (CXCL9)

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Product Details

Catalogue Number: 250-18
Description:
Recombinant Murine MIG (CXCL9)

MIG, a CXC chemokine, is produced by IFN-γ stimulated monocytes, macrophages and endothelial cells.  It signals through the CXCR3 receptor.  MIG selectively chemoattracts Th1 lymphocytes, and also exerts other activities, including inhibition of tumor growth, angiogenesis, and inhibition of colony formation of hematopoietic progenitors.  Human MIG is active on murine cells.  Recombinant Murine MIG is a 12.2 kDa protein containing 105 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines.

Source: E.coli

Synonyms: Monokine Induced by Interferon-gamma, CXCL9

AA Sequence: TLVIRNARCS CISTSRGTIH YKSLKDLKQF APSPNCNKTE IIATLKNGDQ TCLDPDSANV KKLMKEWEKK INQKKKQKRG KKHQKNMKNR KPKTPQSRRR SRKTT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 50.0-150.0 ng/ml.

Calculated Molecular Weight: 12.2 kDa

Accession Number: P18340

Gene ID: 17329

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

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Pein, M
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Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs
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Nature Communications; 11(1) pg1494
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CCL21/CCR7 axis regulating juvenile cartilage repair can enhance cartilage healing in adults.
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