Recombinant Murine TARC (CCL17) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-43 Description: TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Murine TARC (CCL17) is an 7.9 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Thymus and Activation Regulated Chemokine, CCL17, ABCD-2 AA Sequence: ARATNVGREC CLDYFKGAIP IRKLVSWYKT SVECSRDAIV FLTVQGKLIC ADPKDKHVKK AIRLVKNPRP Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract murine BW5147.3 thymic lymphoma cells. The ED50 for this effect is 10-40 ng/ml. Calculated Molecular Weight: 7.9 kDa Accession Number: Reviewed Data Unavailable Gene ID: 20295 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Jacob, J Title Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment. Citation Molecular therapy. Methods & clinical development; 20 pg324-336 PubMed Id 33511246 First Author Sakai, R Title Tocilizumab monotherapy uncovered the role of the CCL22/17-CCR4+ Treg axis during remission of crescentic glomerulonephritis. Citation Clinical & translational immunology; 9(11) pge1203 PubMed Id 33163184
