Chemokines

Recombinant Murine TARC (CCL17)

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Product Details

Catalogue Number: 250-43
Description:
Recombinant Murine TARC (CCL17)

TARC, a CC chemokine, is predominantly produced by dendritic cells in the thymus, and signals through the CCR4 receptor. TARC is chemotactic towards T cells. Recombinant Murine TARC (CCL17) is an 7.9 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Thymus and Activation Regulated Chemokine, CCL17, ABCD-2

AA Sequence: ARATNVGREC CLDYFKGAIP IRKLVSWYKT SVECSRDAIV FLTVQGKLIC ADPKDKHVKK AIRLVKNPRP

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract murine BW5147.3 thymic lymphoma cells. The ED50 for this effect is 10-40 ng/ml.

Calculated Molecular Weight: 7.9 kDa

Accession Number: Reviewed Data Unavailable

Gene ID: 20295

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Jacob, J
Title
Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment.
Citation
Molecular therapy. Methods & clinical development; 20 pg324-336
PubMed Id
First Author
Sakai, R
Title
Tocilizumab monotherapy uncovered the role of the CCL22/17-CCR4+ Treg axis during remission of crescentic glomerulonephritis.
Citation
Clinical & translational immunology; 9(11) pge1203
PubMed Id