Recombinant Human CTACK (CCL27) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-54 Description: CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant Human CTACK is a 10.2 kDa protein containing 88 amino acid residues. Source: E.coli Synonyms: Cutaneous T-cell Attracting Chemokine, CCL27, ALP, Skinkine, Eskine AA Sequence: FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract CXCR3 transfected cells using a concentration of 10.0-100.0 ng/ml. Calculated Molecular Weight: 10.2 kDa Accession Number: Q9Y4X3 Gene ID: 10850 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Lee, A W Title A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citation The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed Id 31167786 First Author Alenazi, Y Title Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Citation Scientific Reports; 8(1) pg6333 PubMed Id 29679010 First Author Buskermolen, J K Title Stimulation of oral fibroblast chemokine receptors identifies CCR3 and CCR4 as potential wound healing targets. Citation Journal of Cellular Physiology; 232(11) pg2996-3005 PubMed Id 28387445
