Chemokines

Recombinant Human CTACK (CCL27)

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Product Details

Catalogue Number: 300-54
Description:
Recombinant Human CTACK (CCL27)

CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant Human CTACK is a 10.2 kDa protein containing 88 amino acid residues.

Source: E.coli

Synonyms: Cutaneous T-cell Attracting Chemokine, CCL27, ALP, Skinkine, Eskine

AA Sequence: FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract CXCR3 transfected cells using a concentration of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 10.2 kDa

Accession Number: Q9Y4X3

Gene ID: 10850

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

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First Author
Lee, A W
Title
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
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The Journal of Biological Chemistry; 294(29) pg11199-11212
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Alenazi, Y
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Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
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Scientific Reports; 8(1) pg6333
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