Recombinant Human LD78β (CCL3L1) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-56 Description: LD78β is a CC chemokine that is closely related to MIP-1α. It signals through the CCR5 receptor and the β-chemokine receptor, D6. LD78β has been shown to exhibit potent activity in HIV suppression assays. Recombinant Human LD78β is a 7.7 kDa protein containing 70 amino acid residues, including the four conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: CCL3L1 AA Sequence: APLAADTPTA CCFSYTSRQI PQNFIADYFE TSSQCSKPSV IFLTKRGRQV CADPSEEWVQ KYVSDLELSA Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract mouse BaF3 cells expressing the CCR5 receptor using a concentration range of 5.0-25.0 ng/ml. Calculated Molecular Weight: 7.7 kDa Accession Number: P16619 Gene ID: 6349 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Lee, A W Title A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citation The Journal of Biological Chemistry; 294(29) pg11199-11212 PubMed Id 31167786 First Author Alenazi, Y Title Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets. Citation Scientific Reports; 8(1) pg6333 PubMed Id 29679010 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871
