Recombinant Human IFN-α (2a) 0 ReviewsSubmit a Review Product Details Catalog Number: 300-02AA Description: Proteins of this family play an important role in inducing non‐specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNα is an acid stable molecule that signals through IFNα/βR, which is also used by IFN‐β. Both IFNs have similar anti‐viral activity and regulate expression of MHC class I antigens. IFN‐α contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant Human IFN‐α (2a) is a 19.3 kDa protein containing 166 amino acid residues. Source: E.coli Synonyms: Interferon alpha‐2, Interferon alpha A, Type I interferon AA Sequence: MCDLPQTHSL GSRRTLMLLA QMRKISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by a cytotoxicity assay using human TF-1 cells. This product has been tested against the WHO standard. International Unit information can be found here. Calculated Molecular Weight: 19.3 kDa Accession Number: P01563 Gene ID: 3440 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest AIDS/HIV Angiogenesis/Cardiovascular Immune System Allergy Proliferation
