Chemokine

Recombinant Human MEC (CCL28)

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Product Details

Catalogue Number: 300-57
Description:


Recombinant Human MEC (CCL28)

MEC is a secreted CC chemokine expressed primarily by epithelial cells of the bronchioles, salivary gland, mammary gland and colon. MEC signals through the CCR10 receptor, and chemoattracts resting CD4, CD8T-cells and eosinophils. MEC contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines. Recombinant Human MEC is a 12.3 kDa protein containing 108 amino acid residues.

Source: E.coli

Synonyms: Mucosae-associated Epithelial Chemokine, CCL28, CCK-1

AA Sequence: SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human lymphocytes using a concentration range of 1.0-10.0 ng/ml.

Calculated Molecular Weight: 12.3 kDa

Accession Number: Q9NRJ3

Gene ID: 56477

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Karlsson, C
Title
Identification of the chemokine CCL28 as a growth and survival factor for human hematopoietic stem and progenitor cells.
Citation
Blood; 121(19) pg3838-42, S1-15
PubMed Id
First Author
Mei, H E
Title
Steady-state generation of mucosal IgA+ plasmablasts is not abrogated by B-cell depletion therapy with rituximab.
Citation
Blood; 116(24) pg5181-90
PubMed Id
First Author
Singh, K
Title
Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities.
Citation
Scientific Reports; 7(1) pg4267
PubMed Id