Chemokine

Recombinant Murine MIP-1γ (CCL9/10)

Product Details

Catalogue Number: 250-12
Description:

MIP-1γ is a CC chemokine found in murine blood and a wide variety of murine tissues, with no known human homolog.  MIP-1γ signals through the CCR1 receptor.  MIP-1γ chemoattracts neutrophils, and also inhibits colony formation of bone marrow myeloid immature progenitors.  MIP-1γ contains six cysteines, including the four highly conserved cysteine residues present in CC chemokines.  Recombinant Murine MIP-1γ is an 11.6 kDa protein containing 101 amino acid residues.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-1γ, CCL9/10, MRP2, CCF18

AA Sequence: QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10.0 ng/ml.

Calculated Molecular Weight: 11.6 kDa

Accession Number: P51670

Gene ID: 20308

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Galeano Niño, J L
Title
Cytotoxic T cells swarm by homotypic chemokine signalling.
Citation
eLIFE; 9
PubMed Id
First Author
He, H
Title
Aging-induced IL27Ra signaling impairs hematopoietic stem cells.
Citation
Blood; 136(2) pg183-198
PubMed Id
First Author
Yagawa, Y
Title
Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy.
Citation
Scientific Reports; 7(1) pg15996
PubMed Id