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Growth Factors & Cytokines
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- Recombinant Human IL-11
| First Author | Title | Citation | Date | Pubmed | |||||||||
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| Purton, L E | All-trans retinoic acid delays the differentiation of primitive hematopoietic precursors (lin-c-kit+Sca-1(+)) while enhancing the terminal maturation of committed granulocyte/monocyte progenitors. | Blood; 94(2) pg483-95 | 15 Jul 1999 |
10397716 Show Usages |
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| Schernthaner, G H | Expression, epitope analysis, and functional role of the LFA-2 antigen detectable on neoplastic mast cells. | Blood; 98(13) pg3784-92 | 15 Dec 2001 |
11739187 Show Usages |
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| Ito, C Y | Hematopoietic stem cell and progenitor defects in Sca-1/Ly-6A-null mice. | Blood; 101(2) pg517-23 | 15 Jan 2003 |
12393491 Show Usages |
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| Liu, B | Disruption of Smad5 gene leads to enhanced proliferation of high-proliferative potential precursors during embryonic hematopoiesis. | Blood; 101(1) pg124-33 | 1 Jan 2003 |
12393578 Show Usages |
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| Varnum-Finney, B | Combined effects of Notch signaling and cytokines induce a multiple log increase in precursors with lymphoid and myeloid reconstituting ability. | Blood; 101(5) pg1784-9 | 1 Mar 2003 |
12411302 Show Usages |
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| Klarmann, K | Identification of in vitro growth conditions for c-Kit-negative hematopoietic stem cells. | Blood; 102(9) pg3120-8 | 1 Nov 2003 |
12855562 Show Usages |
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| Kerrigan, S W | Caspase-12: a developmental link between G-protein-coupled receptors and integrin alphaIIbbeta3 activation. | Blood; 104(5) pg1327-34 | 1 Sep 2004 |
15059849 Show Usages |
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| Hadland, B K | A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. | Blood; 104(10) pg3097-105 | 15 Nov 2004 |
15251982 Show Usages |
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| Modlich, U | Cell-culture assays reveal the importance of retroviral vector design for insertional genotoxicity. | Blood; 108(8) pg2545-53 | 15 Oct 2006 |
16825499 Show Usages |
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| Ghinassi, B | The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor. | Blood; 109(4) pg1460-71 | 15 Feb 2007 |
17038527 Show Usages |
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| Piloto, O | Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways. | Blood; 109(4) pg1643-52 | 15 Feb 2007 |
17047150 Show Usages |
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| Tober, J | The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis. | Blood; 109(4) pg1433-41 | 15 Feb 2007 |
17062726 Show Usages |
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| Maroney, S A | Active tissue factor pathway inhibitor is expressed on the surface of coated platelets. | Blood; 109(5) pg1931-7 | 1 Mar 2007 |
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| Dallas, M H | Enhanced T-cell reconstitution by hematopoietic progenitors expanded ex vivo using the Notch ligand Delta1. | Blood; 109(8) pg3579-87 | 15 Apr 2007 |
17213287 Show Usages |
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| Chen, Z | The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway. | Blood; 110(1) pg171-9 | 1 Jul 2007 |
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| Eto, K | The WAVE2/Abi1 complex differentially regulates megakaryocyte development and spreading: implications for platelet biogenesis and spreading machinery. | Blood; 110(10) pg3637-47 | 15 Nov 2007 |
17664349 Show Usages |
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| Varnum-Finney, B | Notch target Hes5 ensures appropriate Notch induced T- versus B-cell choices in the thymus. | Blood; 111(5) pg2615-20 | 1 Mar 2008 |
18048645 Show Usages |
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| Takayama, N | Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors. | Blood; 111(11) pg5298-306 | 1 Jun 2008 |
18388179 Show Usages |
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| Arendt, B K | Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2. | Blood; 112(5) pg1931-41 | 1 Sep 2008 |
18567838 Show Usages |
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| Porter, C C | Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection. | Blood; 112(12) pg4466-74 | 1 Dec 2008 |
18587011 Show Usages |
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| Jeanpierre, S | BMP4 regulation of human megakaryocytic differentiation is involved in thrombopoietin signaling. | Blood; 112(8) pg3154-63 | 15 Oct 2008 |
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| Cheng, E | Role for MKL1 in megakaryocytic maturation. | Blood; 113(12) pg2826-34 | 19 Mar 2009 |
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| Yu, C | Retinoic acid enhances the generation of hematopoietic progenitors from human embryonic stem cell-derived hemato-vascular precursors. | Blood; 116(23) pg4786-94 | 2 Dec 2010 |
20427702 Show Usages |
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| Halene, S | Serum response factor is an essential transcription factor in megakaryocytic maturation. | Blood; 116(11) pg1942-50 | 16 Sep 2010 |
20525922 Show Usages |
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| Perna, F | Depletion of L3MBTL1 promotes the erythroid differentiation of human hematopoietic progenitor cells: possible role in 20q- polycythemia vera. | Blood; 116(15) pg2812-21 | 14 Oct 2010 |
20585043 Show Usages |
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| Grassinger, J | Phenotypically identical hemopoietic stem cells isolated from different regions of bone marrow have different biologic potential. | Blood; 116(17) pg3185-96 | 28 Oct 2010 |
20631378 Show Usages |
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| Starck, J | Inducible Fli-1 gene deletion in adult mice modifies several myeloid lineage commitment decisions and accelerates proliferation arrest and terminal erythrocytic differentiation. | Blood; 116(23) pg4795-805 | 2 Dec 2010 |
20733157 Show Usages |
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| Kis, L L | STAT6 signaling pathway activated by the cytokines IL-4 and IL-13 induces expression of the Epstein-Barr virus-encoded protein LMP-1 in absence of EBNA-2: implications for the type II EBV latent gene expression in Hodgkin lymphoma. | Blood; 117(1) pg165-74 | 6 Jan 2011 |
20876453 Show Usages |
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| Maetzig, T | Polyclonal fluctuation of lentiviral vector-transduced and expanded murine hematopoietic stem cells. | Blood; 117(11) pg3053-64 | 17 Mar 2011 |
21248062 Show Usages |
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| Pospori, C | Specificity for the tumor-associated self-antigen WT1 drives the development of fully functional memory T cells in the absence of vaccination. | Blood; 117(25) pg6813-24 | 23 Jun 2011 |
21447831 Show Usages |
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| Kubovcakova, L | Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model. | Blood; 121(7) pg1188-99 | 14 Feb 2013 |
23264594 Show Usages |
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| Sportoletti, P | The human NPM1 mutation A perturbs megakaryopoiesis in a conditional mouse model. | Blood; 121(17) pg3447-58 | 25 Apr 2013 |
23435463 Show Usages |
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| Laperrousaz, B | Primitive CML cell expansion relies on abnormal levels of BMPs provided by the niche and on BMPRIb overexpression. | Blood; 122(23) pg3767-77 | 28 Nov 2013 |
24100446 Show Usages |
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| Dahlin, J S | Lin- CD34hi CD117int/hi FcεRI+ cells in human blood constitute a rare population of mast cell progenitors. | Blood; 127(4) pg383-91 | 28 Jan 2016 |
26626992 Show Usages |
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| Goff, J P | Influence of cytokines on the growth kinetics and immunophenotype of daughter cells resulting from the first division of single CD34(+)Thy-1(+)lin- cells. | Blood; 92(11) pg4098-107 | 1 Dec 1998 |
9834215 Show Usages |
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| Wölfler, A | Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors. | Blood; 116(20) pg4116-25 | 18 Nov 2010 |
20807890 Show Usages |
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| Wölfler, A | Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors. | Blood; 116(20) pg4116-25 | 18 Nov 2010 |
20807890 Show Usages |
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| Somervaille, T C | Identification and characterization of leukemia stem cells in murine MLL-AF9 acute myeloid leukemia. | Cancer Cell; 10(4) pg257-68 | 0 Oct 2006 |
17045204 Show Usages |
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| Noyan, F | Induced transgene expression for the treatment of solid tumors by hematopoietic stem cell-based gene therapy. | Cancer Gene Therapy; 19(5) pg352-7 | 0 May 2012 |
22402626 Show Usages |
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| Shah, N | Clonal variation in the B-lineage acute lymphoblastic leukemia response to multiple cytokines and bone marrow stromal cells. | Cancer Research; 61(13) pg5268-74 | 1 Jul 2001 |
11431369 Show Usages |
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| Hemminki, A | Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression. | Cancer Research; 63(4) pg847-53 | 15 Feb 2003 |
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| Forsberg, E C | New evidence supporting megakaryocyte-erythrocyte potential of flk2/flt3+ multipotent hematopoietic progenitors. | Cell; 126(2) pg415-26 | 28 Jul 2006 |
16873070 Show Usages |
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| Bock, C | Reference Maps of human ES and iPS cell variation enable high-throughput characterization of pluripotent cell lines. | Cell; 144(3) pg439-52 | 4 Feb 2011 |
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| Lu, S | Platelets generated from human embryonic stem cells are functional in vitro and in the microcirculation of living mice. | Cell Research; 21(3) pg530-45 | 0 Mar 2011 |
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| Hanazono, Y | In vivo selective expansion of gene-modified hematopoietic cells in a nonhuman primate model. | Gene Therapy; 9(16) pg1055-64 | 0 Aug 2002 |
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| Rivron, N C | Blastocyst-like structures generated solely from stem cells. | Nature; 557(7703) pg106-111 | 0 May 2018 |
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| Grover, A | Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells. | Nature Communications; 7 pg11075 | 24 Mar 2016 |
27009448 Show Usages |
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| Latham, S L | Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia. | Nature Communications; 9(1) pg4250 | 12 Oct 2018 |
30315159 Show Usages |
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| Junk, D J | Oncostatin M promotes cancer cell plasticity through cooperative STAT3-SMAD3 signaling. | Oncogene; 36(28) pg4001-4013 | 13 Jul 2017 |
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| Balduini, A | In vitro megakaryocyte differentiation and proplatelet formation in Ph-negative classical myeloproliferative neoplasms: distinct patterns in the different clinical phenotypes. | PLoS ONE; 6(6) pge21015 | 0 2011 |
21698292 Show Usages |
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| Suman, P | AP-1 transcription factors, mucin-type molecules and MMPs regulate the IL-11 mediated invasiveness of JEG-3 and HTR-8/SVneo trophoblastic cells. | PLoS ONE; 7(1) pge29745 | 0 2012 |
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| Dahlke, C | A microRNA encoded by Kaposi sarcoma-associated herpesvirus promotes B-cell expansion in vivo. | PLoS ONE; 7(11) pge49435 | 0 2012 |
23185331 Show Usages |
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| MacLean, G A | Downregulation of Endothelin Receptor B Contributes to Defective B Cell Lymphopoiesis in Trisomy 21 Pluripotent Stem Cells. | Scientific Reports; 8(1) pg8001 | 22 May 2018 |
29789608 Show Usages |
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| D'Souza, S S | GSK3β Inhibition Promotes Efficient Myeloid and Lymphoid Hematopoiesis from Non-human Primate-Induced Pluripotent Stem Cells. | Stem Cell Reports; 6(2) pg243-56 | 9 Feb 2016 |
26805448 Show Usages |
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| Wang, H | MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1. | Stem Cell Reports; 10(2) pg447-460 | 13 Feb 2018 |
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| Kauts, M | Rapid Mast Cell Generation from Gata2 Reporter Pluripotent Stem Cells. | Stem Cell Reports; 11(4) pg1009-1020 | 9 Oct 2018 |
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| Garcia-Alegria, E | Early Human Hemogenic Endothelium Generates Primitive and Definitive Hematopoiesis In Vitro. | Stem Cell Reports; 11(5) pg1061-1074 | 13 Nov 2018 |
30449319 Show Usages |
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| Martinez, A F | Enabling Large-Scale Ex Vivo Production of Megakaryocytes from CD34+ Cells Using Gas-Permeable Surfaces. | Stem Cells Translational Medicine; 8(7) pg658-670 | 1 Jul 2019 |
30848565 Show Usages |
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| Yan, D | Bovine lactoferricin-induced anti-inflammation is, in part, via up-regulation of interleukin-11 by secondary activation of STAT3 in human articular cartilage. | The Journal of Biological Chemistry; 288(44) pg31655-69 | 1 Nov 2013 |
24036113 Show Usages |
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| An, B | Definition of the native and denatured type II collagen binding site for fibronectin using a recombinant collagen system. | The Journal of Biological Chemistry; 289(8) pg4941-51 | 21 Feb 2014 |
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| An, B | Recombinant Collagen Engineered to Bind to Discoidin Domain Receptor Functions as a Receptor Inhibitor. | The Journal of Biological Chemistry; 291(9) pg4343-55 | 26 Feb 2016 |
26702058 Show Usages |
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| Bluteau, D | Thrombocytopenia-associated mutations in the ANKRD26 regulatory region induce MAPK hyperactivation. | The Journal of Clinical Investigation; 124(2) pg580-91 | 0 Feb 2014 |
24430186 Show Usages |
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| Wang, S | JAK2-binding long noncoding RNA promotes breast cancer brain metastasis. | The Journal of Clinical Investigation; 127(12) pg4498-4515 | 1 Dec 2017 |
29130936 Show Usages |
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| Coffield, V M | Galpha13 mediates a signal that is essential for proliferation and survival of thymocyte progenitors. | The Journal of Experimental Medicine; 200(10) pg1315-24 | 15 Nov 2004 |
15534370 Show Usages |
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| Dallas, M H | Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells. | The Journal of Experimental Medicine; 201(9) pg1361-6 | 2 May 2005 |
15851488 Show Usages |
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| Purton, L E | RARgamma is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation. | The Journal of Experimental Medicine; 203(5) pg1283-93 | 15 May 2006 |
16682494 Show Usages |
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| Nishikii, H | Metalloproteinase regulation improves in vitro generation of efficacious platelets from mouse embryonic stem cells. | The Journal of Experimental Medicine; 205(8) pg1917-27 | 4 Aug 2008 |
18663123 Show Usages |
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| Yu, L | SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis. | The Journal of Experimental Medicine; 207(6) pg1183-95 | 7 Jun 2010 |
20457756 Show Usages |
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| Thiollier, C | Characterization of novel genomic alterations and therapeutic approaches using acute megakaryoblastic leukemia xenograft models. | The Journal of Experimental Medicine; 209(11) pg2017-31 | 22 Oct 2012 |
23045605 Show Usages |
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| Berres, M | BRAF-V600E expression in precursor versus differentiated dendritic cells defines clinically distinct LCH risk groups. | The Journal of Experimental Medicine; 211(4) pg669-83 | 7 Apr 2014 |
24638167 Show Usages |
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| Lyons, J J | ERBIN deficiency links STAT3 and TGF-β pathway defects with atopy in humans. | The Journal of Experimental Medicine; 214(3) pg669-680 | 6 Mar 2017 |
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| van Beek, J | Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation. | Journal of immunology (Baltimore, Md. : 1950); 174(4) pg2353-65 | 15 Feb 2005 |
15699172 Show Usages |
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| Douville, R N | Human metapneumovirus elicits weak IFN-gamma memory responses compared with respiratory syncytial virus. | Journal of immunology (Baltimore, Md. : 1950); 176(10) pg5848-55 | 15 May 2006 |
16670291 Show Usages |
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| Hagn, M | Human B cells secrete granzyme B when recognizing viral antigens in the context of the acute phase cytokine IL-21. | Journal of immunology (Baltimore, Md. : 1950); 183(3) pg1838-45 | 1 Aug 2009 |
19592644 Show Usages |
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| Gurfein, B T | IL-11 regulates autoimmune demyelination. | Journal of immunology (Baltimore, Md. : 1950); 183(7) pg4229-40 | 1 Oct 2009 |
19734214 Show Usages |
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| Lin, A | Rhesus Macaque Myeloid-Derived Suppressor Cells Demonstrate T Cell Inhibitory Functions and Are Transiently Increased after Vaccination. | Journal of immunology (Baltimore, Md. : 1950); 200(1) pg286-294 | 1 Jan 2018 |
29180488 Show Usages |
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| Metcalf, D | Stem cell factor can stimulate the formation of eosinophils by two types of murine eosinophil progenitor cells. | Stem cells (Dayton, Ohio); 20(5) pg460-9 | 0 2002 |
12351816 Show Usages |
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| Gammaitoni, L | Serial transplantations in nonobese diabetic/severe combined immunodeficiency mice of transduced human CD34+ cord blood cells: efficient oncoretroviral gene transfer and ex vivo expansion under serum-free conditions. | Stem cells (Dayton, Ohio); 24(5) pg1201-12 | 0 May 2006 |
16410386 Show Usages |
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| Yao, H | Identification of high proliferative potential precursors with hemangioblastic activity in the mouse aorta-gonad- mesonephros region. | Stem cells (Dayton, Ohio); 25(6) pg1423-30 | 0 Jun 2007 |
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| Matsumura-Takeda, K | CD41+/CD45+ cells without acetylcholinesterase activity are immature and a major megakaryocytic population in murine bone marrow. | Stem cells (Dayton, Ohio); 25(4) pg862-70 | 0 Apr 2007 |
17420226 Show Usages |
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| Fleenor, C J | Contrasting roles for C/EBPα and Notch in irradiation-induced multipotent hematopoietic progenitor cell defects. | Stem cells (Dayton, Ohio); 33(4) pg1345-58 | 0 Apr 2015 |
25546133 Show Usages |
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| Abbonante, V | Thrombopoietin/TGF-β1 Loop Regulates Megakaryocyte Extracellular Matrix Component Synthesis. | Stem cells (Dayton, Ohio); 34(4) pg1123-33 | 0 Apr 2016 |
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| Goff, J P | Synergistic effects of hepatocyte growth factor on human cord blood CD34+ progenitor cells are the result of c-met receptor expression. | Stem cells (Dayton, Ohio); 14(5) pg592-602 | 0 Sep 1996 |
8888500 Show Usages |
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| Muszynski, K W | Raf-1 protein is required for growth factor-induced proliferation of primitive hematopoietic progenitors stimulated with synergistic combinations of cytokines. | Stem cells (Dayton, Ohio); 15(1) pg63-72 | 0 1997 |
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| Seita, J | Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction. | Proceedings of the National Academy of Sciences of the United States of America; 104(7) pg2349-54 | 13 Feb 2007 |
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| Schiedlmeier, B | HOXB4's road map to stem cell expansion. | Proceedings of the National Academy of Sciences of the United States of America; 104(43) pg16952-7 | 23 Oct 2007 |
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| Valamehr, B | Hydrophobic surfaces for enhanced differentiation of embryonic stem cell-derived embryoid bodies. | Proceedings of the National Academy of Sciences of the United States of America; 105(38) pg14459-64 | 23 Sep 2008 |
18791068 Show Usages |
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| Roy, A | Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21. | Proceedings of the National Academy of Sciences of the United States of America; 109(43) pg17579-84 | 23 Oct 2012 |
23045701 Show Usages |
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| Wang, X | Engineering and use of (32)P-labeled human recombinant interleukin-11 for receptor binding studies. | European journal of biochemistry; 269(1) pg61-8 | 0 Jan 2002 |
11784299 Show Usages |
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| Thornhill, S I | Self-inactivating gammaretroviral vectors for gene therapy of X-linked severe combined immunodeficiency. | Molecular therapy : the journal of the American Society of Gene Therapy; 16(3) pg590-8 | 0 Mar 2008 |
18180772 Show Usages |
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| Zychlinski, D | Physiological promoters reduce the genotoxic risk of integrating gene vectors. | Molecular therapy : the journal of the American Society of Gene Therapy; 16(4) pg718-25 | 0 Apr 2008 |
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| Kustikova, O S | Cell-intrinsic and vector-related properties cooperate to determine the incidence and consequences of insertional mutagenesis. | Molecular therapy : the journal of the American Society of Gene Therapy; 17(9) pg1537-47 | 0 Sep 2009 |
19532134 Show Usages |
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| Modlich, U | Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors. | Molecular therapy : the journal of the American Society of Gene Therapy; 17(11) pg1919-28 | 0 Nov 2009 |
19672245 Show Usages |
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