Recombinant Human MCP-1 (CCL2) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-04 Description: The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-1 is an 8.6 kDa protein containing 76 amino acid residues, including the four highly conserved cysteine residues present in the CC chemokines. Source: E.coli Synonyms: Monocyte Chemotactic Protein-1, CCL2, MCAF, JE (murine) AA Sequence: QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration range of 10.0-100.0 ng/ml. Calculated Molecular Weight: 8.6 kDa Accession Number: P13500 Gene ID: 6347 crossreactivity: Bacteria, Chicken, Hamster, Human, Human + Mouse, Human + Parasite, Human + Rat, Monkey, Mouse, Pig, Rat References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest COVID-19 Angiogenesis/Cardiovascular Cancer Chemotaxis Immune System Inflammation Neurobiology Wound Healing Allergy product.subtitle.recentcitations First Author Pontejo, S M Title Two glycosaminoglycan-binding domains of the mouse cytomegalovirus-encoded chemokine MCK-2 are critical for oligomerization of the full-length protein. Citation The Journal of Biological Chemistry; 292(23) pg9613-9626 PubMed Id 28432120 First Author Chen, T Title Spinal microglial motility is independent of neuronal activity and plasticity in adult mice. Citation Molecular Pain; 6 pg19 PubMed Id 20380706 First Author Zhang, Y Title A new antagonist for CCR4 attenuates allergic lung inflammation in a mouse model of asthma. Citation Scientific Reports; 7(1) pg15038 PubMed Id 29118379