Biotinylated Anti-Human TACI 0 ReviewsSubmit a Review Product Details Catalogue Number: 500-P166GBT Description: Source: Polyclonal Goat Preparation: Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hTACI. Anti-Human TACI specific antibody was purified by affinity chromatography and then biotinylated. Immunogen: E.coli-derived, 17.8 kDa Recombinant Human TACI (PeproTech catalog# 310-17) Sandwich ELISA: To detect hTACI by sandwich ELISA (using 100 μl/well antibody solution) a concentration of 0.25 – 1.0 μg/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech’s Polyclonal Anti-Human TACI (500-P166G) as a capture antibody, allows the detection of at least 0.2 – 0.4 ng/well of recombinant hTACI. Western Blot: To detect hTACI by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 µg/ml. Used in conjunction with compatible secondary reagents the detection limit for recombinant hTACI is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions. Note: 1mg will be provided as 2x500μg. crossreactivity: Human References SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Cancer Immune System Inflammation TNF Superfamily product.subtitle.recentcitations First Author Lee, J J Title The murine equivalent of the A181E TACI mutation associated with common variable immunodeficiency severely impairs B-cell function. Citation Blood; 114(11) pg2254-62 PubMed Id 19605846 First Author Salzer, U Title Relevance of biallelic versus monoallelic TNFRSF13B mutations in distinguishing disease-causing from risk-increasing TNFRSF13B variants in antibody deficiency syndromes. Citation Blood; 113(9) pg1967-76 PubMed Id 18981294 First Author Cuss, A K Title Expansion of functionally immature transitional B cells is associated with human-immunodeficient states characterized by impaired humoral immunity. Citation Journal of immunology (Baltimore, Md. : 1950); 176(3) pg1506-16 PubMed Id 16424179
