Recombinant Murine IL-17D
Detalles del Producto
Nùmero de Catalogo
IL‐17D is a disulfide‐linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL‐17 family of structurally‐related cytokines that share a highly conserved C‐terminal region, but differ from one another in their N‐terminal regions and in their distinct biological roles. The six known members of this family, IL‐17A through IL‐17F, are secreted as homodimers. IL‐17D has the ability to stimulate the production of IL‐6, IL‐8 and GM‐CSF, and inhibits hemopoiesis of myeloid progenitor cells in colony‐forming assays. Recombinant Murine IL‐17D is a 20.2 kDa protein consisting of 184 amino acid residues.
MAGALRTGRR PARPRDCADR PEELLEQLYG RLAAGVLSAF HHTLQLGPRE QARNASCPAG GRAADRRFRP PTNLRSVSPW AYRISYDPAR FPRYLPEAYC LCRGCLTGLY GEEDFRFRST PVFSPAVVLR RTAACAGGRS VYAEHYITIP VGCTCVPEPD KSADSANSSM DKLLLGPADR PAGR
≥ 95% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to bind murine IL-17RB Fc Chimera in a functional ELISA.
Calculated Molecular Weight:
Reviewed Data Unavailable
Country Of Origin: USA
Not for human use.