The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Murine MCP-3 is an 8.5 kDa protein containing 74 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Monocyte Chemotactic Protein-3, CCL7, MARC
QPDGPNASTC CYVKKQKIPK RNLKSYRRIT SSRCPWEAVI FKTKKGMEVC AEAHQKWVEE AIAYLDMKTP TPKP
≥ 98% by SDS-PAGE gel and HPLC analyses.
Determined by its ability to chemoattract BaF3 cells expressing human CCR2 receptor using a concentration range of 300-500 ng/ml.
Calculated Molecular Weight:
Not for human use.