Other Proteins

Recombinant Viral MIP-2

Product Details

Catalogue Number: 350-03
Description:

Viral MIP-2 (vMIP-2) is a chemokine analog encoded by the human herpes virus, and has been shown to have antagonist activity towards several chemokine receptors. Recombinant Viral MIP-2 is a 7.9 kDa protein consisting of 70 amino acids, including the four highly conserved cysteine residues present in CC chemokines.

Source: E.coli

Synonyms: Macrophage Inflammatory Protein-2

AA Sequence: LGASWHRPDK CCLGYQKRPL PQVLLSSWYP TSQLCSKPGV IFLTKRGRQV CADKSKDWVK KLMQQLPVTA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by the inhibitory effect on monocyte migration response to human MIP-1 alpha using a concentration range of 1.0µg-10.0µg/ml of viral MIP-2 will inhibit 25ng/ml of human MIP-1 alpha.

Calculated Molecular Weight: 7.9 kDa

Accession Number: Q98157

Gene ID: 4961514

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Yu, J
Title
Generation of an osteoblast-based artificial niche that supports in vitro B lymphopoiesis.
Citation
Experimental & molecular medicine; 49(11) pge400
PubMed Id
First Author
Kovács, M
Title
The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitment.
Citation
The Journal of Experimental Medicine; 211(10) pg1993-2011
PubMed Id
First Author
Singh, U P
Title
Viral macrophage-inflammatory protein-II: a viral chemokine that differentially affects adaptive mucosal immunity compared with its mammalian counterparts.
Citation
Journal of immunology (Baltimore, Md. : 1950); 173(9) pg5509-16
PubMed Id