Chemokines

Recombinant Murine Exodus-2 (CCL21)

Product Details

Catalog Number: 250-13
Description:

Exodus-2 is a CC chemokine that can signal through the CCR7 receptor. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant Murine Exodus-2 is a 12.0 kDa protein containing 110 amino acid residues.

Source: E.coli

Synonyms: CCL21, 6Ckine, SLC

AA Sequence: SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG

Purity: Greater than 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2 using a concentration range of 10.0-100.0 ng/ml.

Note:

1mg will be provided as 2x500μg.

Cross Reactivity:
Bacteria, Human, Leech, Monkey, Mouse, Rat
Research Interest

Country Of Origin: USA

Research Use Only: Not for use in diagnostic or therapeutic procedures.