Recombinant Human PlGF-2 0 ReviewsSubmit a Review Product Details Catalogue Number: 100-56A Description: PlGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-2 is expressed in umbilical vein endothelial cells and placenta. It signals through the VEGFR-1/FLT1 receptor, and stimulates endothelial cell proliferation and migration. PlGF-2 also signals through Neuropilin (NP-1), and can bind with high affinity to heparin. Recombinant Human PlGF-2 is a 34.6 kDa disulfide-linked homodimeric protein of two 152 amino acid polypeptide chains. Source: E.coli Synonyms: Placenta Growth Factor-2, PGFL AA Sequence (monomer): LPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRPLREKMK PERRRPKGRG KRRREKQRPT DCHLCGDAVP RR Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human THP-1 cells of using a concentration range of 5.0-50.0 ng/ml. Calculated Molecular Weight: 34.6 kDa Accession Number: P49763 Gene ID: 5228 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Cancer Immune System Inflammation Stem Cells & Differentiation product.subtitle.recentcitations First Author Zhang, L Title Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer. Citation Cell; 181(2) pg442-459.e29 PubMed Id 32302573
