Recombinant Murine MIP-3α (CCL20) 0 ReviewsSubmit a Review Product Details Catalogue Number: 250-27 Description: MIP-3α is a CC chemokine, expressed in the liver, lymph nodes, appendix, PBL and lungs that can signal through the CCR6 receptor. MIP-3α is chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells, and inhibits colony formation of bone marrow myeloid immature progenitors. Recombinant Murine MIP-3α is a 7.9 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Source: E.coli Synonyms: Macrophage Inflammatory Protein-3α, CCL20, LARC, Exodus-1 AA Sequence: ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract murine CCR6-transfected HEK293 cells using a concentration range of 0.1-10.0 ng/ml Calculated Molecular Weight: 7.9 kDa Accession Number: O89093 Gene ID: 20297 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Human, Human + Mouse, Mouse References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Chemotaxis Immune System Wound Healing product.subtitle.recentcitations First Author Yagawa, Y Title Systematic Screening of Chemokines to Identify Candidates to Model and Create Ectopic Lymph Node Structures for Cancer Immunotherapy. Citation Scientific Reports; 7(1) pg15996 PubMed Id 29167448 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871 First Author Velázquez, F Title CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo. Citation Journal of immunology (Baltimore, Md. : 1950); 196(3) pg1305-1316 PubMed Id 26700769
