Recombinant Human FGF-17

Detalles del Producto

Nùmero de Catalogo 100-27

Descripcion

FGF-17 is a heparin-binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-17 signals through FGFR 1c, 2c, 3c, and 4. FGF-17 promotes the induction and patterning of brain development during embryogenesis. Recombinant Human FGF-17 is a 22.7 kDa protein consisting of 195 amino acid residues.

Source: E.coli

Synonyms: Fibroblast Growth Factor-17, FGFH

AA Sequence: MTQGENHPSP NFNQYVRDQG AMTDQLSRRQ IREYQLYSRT SGKHVQVTGR RISATAEDGN KFAKLIVETD TFGSRVRIKG AESEKYICMN KRGKLIGKPS GKSKDCVFTE IVLENNYTAF QNARHEGWFM AFTRQGRPRQ ASRSRQNQRE AHFIKRLYQG QLPFPNHAEK QKQFEFVGSA PTRRTKRTRR PQPLT

Purity: ≥ 95% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED₅₀ is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 10⁵ units/mg.

Calculated Molecular Weight: 22.7 kDa

Accession Number: O60258

Gene ID: 8822

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

Note:

250μg is the largest vial size for this product.
Larger sizes supplied as multiple 250μg vials.

crossreactivity:

Human, Mouse, Rat