Chemokine

Recombinant Human MCP-4 (CCL13)

Product Details

Catalogue Number: 300-24
Description:

The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-4 is an 8.6 kDa protein containing 75 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Source: E.coli

Synonyms: Monocyte Chemotactic Protein-4, CCL13, NCC-1

AA Sequence: QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human monocytes using a concentration of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 8.6 kDa

Accession Number: Q99616

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Tiffany, H L
Title
Identification of CCR8: a human monocyte and thymus receptor for the CC chemokine I-309.
Citation
The Journal of Experimental Medicine; 186(1) pg165-70
PubMed Id
First Author
Lee, A W
Title
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
Citation
The Journal of Biological Chemistry; 294(29) pg11199-11212
PubMed Id
First Author
Alenazi, Y
Title
Genetically engineered two-warhead evasins provide a method to achieve precision targeting of disease-relevant chemokine subsets.
Citation
Scientific Reports; 8(1) pg6333
PubMed Id