Chemokine

Recombinant Murine KC (CXCL1)

0 ReviewsSubmit a Review

Product Details

Catalogue Number: 250-11
Description:

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant Murine KC is a 7.8 kDa protein consisting of 72 amino acids, including the 'ELR' motif common to the CXC chemokine family that binds to CXCR1 or CXCR2.

Source: E.coli

Synonyms: MGSAα, CXCL1, NAP-3, GRO1, GRO/MGSA (human), CINC (rat)

AA Sequence: APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract total human neutrophil population using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 7.8 kDa

Accession Number: P12850

Gene ID: 14825

Note:

1mg will be provided as 2x500μg.

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Frommhold, D
Title
Sialyltransferase ST3Gal-IV controls CXCR2-mediated firm leukocyte arrest during inflammation.
Citation
The Journal of Experimental Medicine; 205(6) pg1435-46
PubMed Id
First Author
Taylor, A
Title
SRF is required for neutrophil migration in response to inflammation.
Citation
Blood; 123(19) pg3027-36
PubMed Id
First Author
Tager, A M
Title
BLTR mediates leukotriene B(4)-induced chemotaxis and adhesion and plays a dominant role in eosinophil accumulation in a murine model of peritonitis.
Citation
The Journal of Experimental Medicine; 192(3) pg439-46
PubMed Id