Recombinant Human PF-4 (CXCL4) 0 ComentariosSubmit a Review Detalles del Producto Nùmero de Catalogo 300-16 Descripcion PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes, and has been shown to inhibit angiogenesis. Recombinant Human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Source: E.coli Synonyms: Platelet Factor-4, CXCL4, Oncostatin A, Ironplact AA Sequence: EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P02776 Gene ID: 5196 Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug) crossreactivity: Bacteria, Human, Mouse, Parasite References PubMed SDS Búsqueda del CoA Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations Primer autor Matsumoto, K Titulo Platelet CXCL4 mediates neutrophil extracellular traps formation in ANCA-associated vasculitis. Citar Scientific Reports; 11(1) pg222 PudMed id 33420306 Primer autor Carvalheiro, T Titulo Induction of Inflammation and Fibrosis by Semaphorin 4A in Systemic Sclerosis. Citar Arthritis & rheumatology (Hoboken, N.J.); 71(10) pg1711-1722 PudMed id 31012544 Primer autor Lee, A W Titulo A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins. Citar The Journal of Biological Chemistry; 294(29) pg11199-11212 PudMed id 31167786
