Chemokines

Recombinant Human MCP-2 (CCL8)

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Product Details

Catalogue Number: 300-15
Description:
Recombinant Human MCP-2 (CCL8)

The MCP proteins are members of the CC chemokine family that signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated Tcells, basophils, NK cells, and immature dendritic cells. The MCP family cross-reacts across species. Recombinant Human MCP-2 is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.

Source: E.coli

Synonyms: Monocyte Chemotactic Protein-2, CCL8, HC14

AA Sequence: QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng/ml.

Calculated Molecular Weight: 8.9 kDa

Accession Number: P80075

Gene ID: 6355

crossreactivity:
Country Of Origin: USA

Not for human use.

Research Interest

product.subtitle.recentcitations

First Author
Bouhaddou, M
Title
The Global Phosphorylation Landscape of SARS-CoV-2 Infection.
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Cell; 182(3) pg685-712.e19
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First Author
Blanco-Melo, D
Title
Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19.
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Cell; 181(5) pg1036-1045.e9
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Lee, A W
Title
A knottin scaffold directs the CXC-chemokine-binding specificity of tick evasins.
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The Journal of Biological Chemistry; 294(29) pg11199-11212
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