Recombinant Human PF-4 (CXCL4) 0 ReviewsSubmit a Review Product Details Catalogue Number: 300-16 Description: PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the α-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes, and has been shown to inhibit angiogenesis. Recombinant Human PF-4 is a 7.8 kDa protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines. Source: E.coli Synonyms: Platelet Factor-4, CXCL4, Oncostatin A, Ironplact AA Sequence: EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses. Biological Activity: Determined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0 ng/ml. Calculated Molecular Weight: 7.8 kDa Accession Number: P02776 Gene ID: 5196 crossreactivity: Bacteria, Human, Mouse, Parasite, Trout References PubMed SDS CoA Search Product Line Country Of Origin: USA Not for human use. Research Interest Angiogenesis/Cardiovascular Chemotaxis Immune System Inflammation Wound Healing product.subtitle.recentcitations First Author Matsumoto, K Title Platelet CXCL4 mediates neutrophil extracellular traps formation in ANCA-associated vasculitis. Citation Scientific Reports; 11(1) pg222 PubMed Id 33420306 First Author Schweickart, V L Title CCR11 is a functional receptor for the monocyte chemoattractant protein family of chemokines. Citation The Journal of Biological Chemistry; 275(13) pg9550-6 PubMed Id 10734104 First Author Singh, K Title Yeast surface display identifies a family of evasins from ticks with novel polyvalent CC chemokine-binding activities. Citation Scientific Reports; 7(1) pg4267 PubMed Id 28655871