Chemokines

Recombinant Human Exodus-2 (CCL21)

Product Details

Catalog Number: 300-35A
Description:

Exodus‐2 is a CC chemokine that signals through the CCR7 receptor. It is expressed in lymphatic endothelial cells, the spleen and appendix. Exodus‐2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus‐2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant Human Exodus‐2 (CCL21) is a 12.2 kDa protein containing 111 amino acid residues.

Source: E.coli

Note: Expressed using different clones, Cat# 300-35 and Cat# 300-35A differ from one another at amino acid positions 100 and 101, where the amino acids arginine (R) and lysine (K) are transposed.

Synonyms: 6Ckine, SLC

AA Sequence: SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2.

Calculated Molecular Weight: 12.2 kDa

Accession Number: O00585

Gene ID: 6366

Research Interest

Country Of Origin: USA

Not for human use.