Recombinant Murine BCA-1/BLC (CXCL13)

Product Details

Catalogue Number: 250-24

Description:

BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor, CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes, and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Murine BLC is a 9.8 kDa protein containing 88 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.

Source: E.coli

Synonyms: B cell Attracting Chemokine-1, CXCL13, BLC (mouse), BLR1 Ligand

AA Sequence: ILEAHYTNLK CRCSGVISTV VGLNIIDRIQ VTPPGNGCPK TEVVIWTKMK KVICVNPRAK WLQRLLRHVQ SKSLSSTPQA PVSKRRAA

Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity: Determined by its ability to chemoattract human B cells.

Calculated Molecular Weight: 9.8 kDa

Accession Number: O55038

Gene ID: 55985

Endotoxin: Endotoxin level is < 0.1 ng/ug of protein (< 1 EU/ug)

crossreactivity:

Human, Mouse,

Country Of Origin: USA

Not for human use.

Research Interest

Chemotaxis

Immune System

Wound Healing

product.subtitle.recentcitations

First Author

Ma, L

Title

ZNF382 controls mouse neuropathic pain via silencer-based epigenetic inhibition of Cxcl13 in DRG neurons.

Citation

The Journal of Experimental Medicine; 218(12)

PubMed Id

34762123

First Author

Cruz-Zárate, D

Title

Myo1g is required for efficient adhesion and migration of activated B lymphocytes to inguinal lymph nodes

Citation

Scientific Reports; 11(1) pg7197

PubMed Id

33785780

First Author

Shi, J

Title

PD-1 Controls Follicular T Helper Cell Positioning and Function.

Citation

Immunity; 49(2) pg264-274.e4

PubMed Id

30076099

Chemokines